See VIDEO included *above*
If you are new to the topic of microbiome and dysbiosis, then please see the introductory video linked below:
Microbiome Dysbiosis (1) Course Overview and Introduction to Major Concepts and Mechanisms
UPDATE February-March 2025: I’ve noticed that some of the videos previously posted/streaming from the Vimeo platform are no longer reliably visible, while at the same time, this Substack platform has progressively allowed for direct uploading/embedding of videos; as such, many of the previously-posted videos are being reloaded directly into the Substack platform for more reliable access and archiving.
Want to see one of my publications that pissed off a lot of FAKE EXPERTS pretending to know something about the gut microbiome?
This is from a really low-quality “integrative medicine” journal.
Want to see another one? This review that I wrote actually resulted in the article getting retracted by the journal editors.
PLOS is a semi-respected journal but somehow this junk science got past their editors until I sent them my review and then the published article was appropriately retracted because it was bunk.
HUMAN MICROBIOME AND DYSBIOSIS IN CLINICAL DISEASE was a continuing medical education (CME) program with accompanying monograph, the entirety of which is included within Inflammation Mastery 4th Edition:
Sample PDF downloads:
Click here to see the first few pages, including the table of contents and index (size: 6 MB)
Click here for a larger sample with photos (size: 43 MB)
My course on “Human Microbiome and Dysbiosis in Clinical Disease” was developed over several years starting formally in 2015-2017 as a continuing medical education (CME) postgraduate online conference joint-accredited for doctors, nurses, and pharmacists:
“American Medical Association Physician's Recognition Award (AMA PRA) Category 1 Statement: This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership … accredited by the ACCME to provide continuing medical education for physicians. …designates this educational activity for a maximum of 30 AMA PRA Category 1 credits.
Nursing Statement: …approved provider of continuing nursing education by the Washington State Nurses Association WSNA A-CNE, an accredited Approver of Continuing Nursing Education.
Pharmacy Statement: …accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. Objectives appropriate for pharmacists.”
I’ve established legitimate expertise on this topic for more than 20 years via clinical experience, post-graduate conference presentations, book publications, and numerous peer-reviewed professional publications.









Dr Alex Vasquez. Reducing pain and inflammation naturally - Part 6: Nutritional and Botanical Treatments Against “Silent Infections” and Gastrointestinal Dysbiosis, Commonly Overlooked Causes of Neuromusculoskeletal Inflammation and Chronic Health Problems. Nutritional Perspectives 2006 Jan
Dr Alex Vasquez. Neuroinflammation in fibromyalgia and CRPS is multifactorial. Nat Rev Rheumatol 2016 Apr;12(4):242. doi: 10.1038/nrrheum.2016.25 pubmed.ncbi.nlm.nih.gov/26935282
Dr Alex Vasquez. Biological plausibility of the gut-brain axis in autism. Ann N Y Acad Sci 2017 Nov;1408(1):5-6. doi: 10.1111/nyas.13516 pubmed.ncbi.nlm.nih.gov/29090837
Dr Alex Vasquez. Musculoskeletal Pain: Expanded Clinical Strategies: Printed monograph approved for ACCME PRA-1 Continuing Medical Education ncbi.nlm.nih.gov/nlmcatalog/101633549 Published by: Institute for Functional Medicine. 2008 May
Dr Alex Vasquez. Mitochondrial Medicine Arrives to Prime Time in Clinical Care: Nutritional Biochemistry and Mitochondrial Hyperpermeability ("Leaky Mitochondria") Meet Disease Pathogenesis and Clinical Interventions. Integr Med (Encinitas) 2014 Aug;13(4):44-9 pubmed.ncbi.nlm.nih.gov/26770108
Dr Alex Vasquez. Reply to "role of Western diet in inflammatory autoimmune diseases" by Manzel et al. In current allergy and asthma reports (volume 14, issue 1, January 2014). Curr Allergy Asthma Rep 2014 Aug;14(8):454. doi: 10.1007/s11882-014-0454-4 pubmed.ncbi.nlm.nih.gov/24947682
Dr Alex Vasquez. Correspondence regarding Cutshall, Bergstrom, Kalish's "Evaluation of a functional medicine approach to treating fatigue, stress, and digestive issues in women" in Complement Ther Clin Pract 2016 May. Complement Ther Clin Pract 2018 May;31:332-333. doi: 10.1016/j.ctcp.2016.10.001 pubmed.ncbi.nlm.nih.gov/27814977
Dr Alex Vasquez. The Microbiome Arrives to Prime Time in Primary Care, Implications for the Anti-Dysbiotic Treatment of Fibromyalgia. Nutritional Perspectives 2015 Oct
Dr Alex Vasquez. Translating Microbiome (Microbiota) and Dysbiosis Research into Clinical Practice: The 20-Year Development of a Structured Approach that Gives Actionable Form to Intellectual Concepts. International Journal of Human Nutrition and Functional Medicine 2015 Jun
Update 2025: All videos are being re-uploaded in Feb-May 2025 to provide direct and reliable access through the substack platform:
Can you answer these 10 questions on dysbiosis and microbiome?
VIDEO with discussion of QUESTIONS and ANSWERS 1-5 with Test-Taking Strategies
QUESTIONS and ANSWERS for Dysbiosis & Microbiome (6-10) with Test-Taking Strategies
Microbiome Dysbiosis (1) Course Overview and Introduction to Major Concepts and Mechanisms
Microbiome Dysbiosis (2) Physiologic and Pathologic Mechanisms of Dysbiosis and Subclinical Microbial Colonizations (VIDEO:1hour,15minutes)
Microbiome Dysbiosis (3) Prototypes of Dysbiosis-Induced Disease (VIDEO:1hour,42minutes=102minutes)
Microbiome Dysbiosis (4) Conceptual Expansion Exploring Clinical Testing, Microbial Relevance and Irrelevance [VIDEO:1hour,18minutes=78minutes]
Microbiome Dysbiosis (5) Microbial Consequences in the Mouth, Oral Cavity [VIDEO:1hour,44minutes=104minutes]
Microbiome Dysbiosis (6) Microbial Imbalances in the Respiratory Tract and Sinuses [VIDEO:1hour,35minutes=95minutes]
Microbiome Dysbiosis (7) Dysbiosis by Location—Genitourinary Tract
Microbiome Dysbiosis (8) Dysbiosis by Location—Blood, Tissue, Parenchymal Dysbioses
Microbiome Dysbiosis (9) Dysbiosis by Location—Skin and Environmental Dysbiosis
MICROBIOME DYSBIOSIS (10) Gut Dysbiosis Prototypes — included above
Gut-Brain axis prototypes — coming soon
Gut-Brain axis solutions — coming soon
The clinical monograph HUMAN MICROBIOME AND DYSBIOSIS IN CLINICAL DISEASE is included within Inflammation Mastery 4th Edition:
Inflammation Mastery 4th Edition: The Colorful and Definitive Guide Toward Health and Vitality and away from the Boredom, Risks, Costs, and Inefficacy of Endless Analgesia, Immunosuppression, and Polypharmacy
Sample PDF downloads:
Click here to see the first few pages, including the table of contents and index (size: 6 MB)
Click here for a larger sample with photos (size: 43 MB)
non plus ultra
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